Apex Legends: Improves gameplay stability
Overwatch: Game may freeze on launching a match
Dungeons 3: Game will crash on startup
Red Dead Redemption 2: Performance improvement when using DLSS is lower compared to previous drivers
Destiny 2: Game may randomly freeze after launching game or during gameplay
Halo Infinite: Increase stability during gameplay

If you're not running into any of the above issues, you'd be fine to skip the hotfix, as it doesn't include anything else of note—there are no security patches, additional game optimizations, or anything else not listed above. The only way to get the hotfix is through a manual download. NVIDIA's GeForce Experience doesn't fetch hotfix releases, nor will you find it when heading to NVIDIA's driver download page