Kane is able to use the world around him to his advantage, creating mayhem in every highly destructible environment; blowing up cars and fuel tanks to efficiently take down pursuers. Creating panic by opening fire in a packed Toyko nightclub, just to use the ensuing chaos to cover his escape and using cover to avoid enemy fire while taking precise aim to shoot down single or multiple enemies.

Providing additional backup, Kane has the option to control a crew of criminal mercenaries to scout new and potentially dangerous locations or take out specific enemies. The optional crew-based combat system allows for added tactical strategy when in heavy gunfight situations enabling Kane to direct a crew member to cover fire at a specific target while sending another crew member to protect his flank position.

One element Kane cannot control is Lynch. Succumbing frequently to psychotic episodes, Lynch flies off the handle at critical moments, foiling Kane's plans. In the two player Co-op mode, players get a split screen glimpse at the world through Lynch's eyes. Players will also have the opportunity to play in the unique online multiplayer mode, supporting up to eight players online. This new multiplayer twist will shake up the online gameplay experience.