In the game the player takes the command chair, directing groups of emergency services teams including police, fire fighters, hostage negotiators, K9 units, ambulance services and search and rescue units. In 25 action-packed, pulse-pounding missions, the player orders units to close roads, tend to the injured, prepare sharpshooters in tense hostage standoffs, contain nuclear disasters, make arrests, put out fires, rescue people trapped in wrecked vehicles and protect civilians and politicians.

Missions are extremely varied with nearly 50 types of units including K9, Special Forces, Firefighting Planes, Helicopters, Nuclear/Biological/Chemical Teams, Psychologists and more. Combined with night and day environments, fully accessible indoor and outdoor environments and settings ranging from urban cityscapes and countrysides, Emergency 2 is a realistic, immersive experience that gives the player an opportunity to be a hero.