1 Select Teleport - Fracture (rune)
2 Select Archon - Arcane Destruction (rune)
3 Hover your mouse over your character
4 Press Teleport and quickly after press Archon

Result: Character becomes Invulerable. No health loss at all, some effects like frozen don't work anymore.

Works in Softcore and in Hardcore. Needs a couple of tries to get it working, but once you have the timing it can easily be reproduced. This is pretty much gamebreaking, I hope to see a hotfix soon.